For years there has been confusion in a group of cutaneous lesions listed under erythema nodosum, erythema induratum, and sarcoid; and there has also been confusion regarding the tuberculids.
Erythema nodosum is generally described as a clean-cut clinical entity. Thus, Pusey1 says erythema nodosum is an acute inflammatory disease of the skin of systemic origin. The lesions consist of multiple painful nodules which disappear in ten days to two weeks, without ulceration. The condition accompanies infectious processes, being most frequently associated with articular rheumatism.
Bazin2 described erythema induratum as painless chronic nodules, of a scrofulous nature. He did not mention ulceration in the condition; but Hutchinson3 pointed out that ulceration occurred.
In 1901, Whitfield4 described two cases, and said that these cases suggested that more than one condition was listed under erythema induratum. The first case presented the usual typical picture of erythema induratum, with ulceration.
WHITMORE ER. TYPE III SARCOID ASSOCIATED WITH INFECTION OF TONSILS AND GUMS. Arch Derm Syphilol. 1925;11(1):56–70. doi:10.1001/archderm.1925.02370010069003
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