Two consecutive cases of urticaria pigmentosa in which an enlarged thymus gland was easily demonstrated by roentgen-ray examination came under my observation.
Three years ago I was asked by Dr. William Harvey Guy to study a case of nodular type of urticaria pigmentosa from an endocrinologic standpoint, and much to our mutual surprise we found a marked hyperplasia of the thymus gland in association with a slight adenopathy of the cervical glands. I was tempted to report this observation at that time. However, it was thought wise to wait and see what other cases might show.
On Sept. 10, 1924, a macular type of urticaria pigmentosa came under my observation with similar findings, and I feel that even though the co-appearance of these two relatively rare conditions may be coincidental, the observation is useful and worthy of record.
The comparative infrequency with which the dermatologist is faced with the thymus
HOLLANDER L. URTICARIA PIGMENTOSA WITH HYPERPLASIA OF THE THYMUS GLAND. Arch Derm Syphilol. 1925;11(5):611–622. doi:10.1001/archderm.1925.02370050034002
Dermatology in JAMA: Read the Latest
Customize your JAMA Network experience by selecting one or more topics from the list below.