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Repeated and constant effort to determine the factor or factors underlying the cause of psoriasis has led to no definite knowledge. Whether this disease is due to a living agent, to nutritional unbalance or to a lack or an excess of certain substances within the affected organism is a moot question, and there may be found supporters of all and any theories concerning the etiology of psoriasis.
We wish to present briefly the results of a study of a number of cases of psoriasis. The fact that fungi imperfecti are the causative agents of a number of dermatologic lesions, as well as our own observations that organisms similar or identical with those found in the lesions were also present in the feces in some such cases, led us to search for organisms of this type in cases of psoriasis.
We have made cultures from the scales, the blood and feces