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August 1925


Arch Derm Syphilol. 1925;12(2):233-234. doi:10.1001/archderm.1925.02370080077005

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Incidental to the recent smallpox epidemic and consequent widespread vaccination, we have seen thirty-five cases presenting unusual dermatologic sequelae. The history in all cases was practically the same. Subsequent to complete healing (as late as six weeks after healing), there appeared an eruption beginning in the vaccination scar as an erythematous, slightly scaly spot. After forty-eight to seventy-two hours, the lesion was sharply marginated, slowly spreading, and the scaling more abundant. Lesions enlarged gradually until they measured from 4 to 8 cm. in diameter. New lesions appeared near the original lesion in about one third of the cases. In one or two cases, confluence of lesions was noted, and in two cases similar lesions appeared in distant parts of the body. The duration varied from four days to three months. We noted no tendency toward spontaneous involution. In one case, the lesions were impetiginous. Direct examination in twenty cases revealed

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