Skin eruptions are fairly common manifestations of bromism, and although several interesting theories have been advanced, nothing is yet known regarding the reason for their appearance. Bromids are excreted very slowly from the body, and the tendency to accumulation explains the slow regression of the bromodermas, even after the drug is stopped. Nervous symptoms, occasionally of an alarming nature, also occur in bromism. Any remedy which would hasten the excretion of bromid should be welcome.
In an article by Wile, Wright and Smith,1 the fact that bromid ingestion hastened the elimination of chlorids in the urine was stressed, and the suggestion made that the process might be reversible; that is, that stored up bromids in the body might be "pushed out" by the mass action of relatively large amounts of chlorid administered.
In a later article, Wile2 reported three cases of bromism in which the patients were treated