In 1922, Hill, White, Moore and Young1 published an interesting article calling attention to the objections of the more common methods of administrating mercury; that is, by mouth, by inunction, intravenously and intramuscularly. At the same time these workers introduced a new drug, which is the disodium salt of hydroxymercurifluorescein, to which they have given the name "flumerin," and they called attention to the nonirritating local qualities and to its low toxicity, thereby recommending it as a drug which can be used advantageously in the intravenous administration of mercury. The drug which was used in this series of patients was donated to one of us (J. F. H.) by Dr. Hugh H. Young and was intended to be used as a routine in the clinic in place of the mercuric salicylate. It was during this general use that it was accidentally discovered to be of such great value in