In a previous communication,1 the authors showed that nonspecific therapy favorably influences the courses of syphilis. It was demonstrated that injections of a 4 per cent, suspension of milk protein in the deep muscles would result in partial or complete involution of some types of secondary and tertiary manifestations of the disease. It was not intimated that injections of a foreign protein are in any way a cure for syphilis, but it was suggested that perhaps the effect of the injections is to stimulate the natural protective forces of the body, which, if true, would indicate that such a therapeutic procedure, in conjunction with other therapy, might prove of value.
The procedure, as carried out, consisted of a preliminary course of six intramuscular (gluteal) injections of a 4 per cent, sterile suspension of milk protein, the injections being given at intervals of two or three days. Upon the completion
GREENBAUM SS, WRIGHT CS. VALUE OF NONSPECIFIC PROTEIN THERAPY IN SYPHILIS: WITH SPECIAL REFERENCE TO ITS EFFECT ON THE WASSERMANN REACTION WHEN USED AS AN ADJUNCT TO NEO-ARSPHENAMIN. Arch Derm Syphilol. 1925;12(6):858–864. doi:10.1001/archderm.1925.02370120088009
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