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January 1926


Arch Derm Syphilol. 1926;13(1):128-130. doi:10.1001/archderm.1926.02370130131015

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Keratosis Follicularis — Darier's Disease. Presented by Dr. Phillips.  F. H., a man, aged 55, a blacksmith, presented a skin eruption which had existed since he was 7 years old, gradually growing worse. Itching and soreness were present, and the odor was offensive. Practically every part of the body showed pigmented macules and papules; however, the only areas showing papillomatous, vegetating, tumor-like growths were the chest, pubic region and shins. These were covered with vegetating masses from which pus exuded on slight pressure. A few areas had broken down to form ulcers, the largest of which was about the size of a half dollar. Many other areas were covered with a brown greasy crust, especially the scalp, ears, axillae, groins and back. The crust over the scalp was not unlike that found in severe cases of seborrhea, except that it was more firmly adherent. The patient's father and one of

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