During the past two years, I have had under observation a case, the outstanding characteristics of which have been a chronic, itching, papular eruption involving the axillae, the pubic region and the breasts. Clinically and histologically this is undoubtedly an example of the rare condition originally described by Fox and Fordyce in 1902.1
Since the original description of this disease, about thirty cases have been reported. Although most of these cases have occurred in neurotic women, some of whom were anemic and poorly nourished, and Whitfield's case was of the visceroptotic type with a colitis and digestive disturbances, in the majority of the cases there were no findings which adequately explained the neurotic condition. For this reason the association of this rare condition with hyperthyroidism in the case reported here is of sufficient interest to warrant placing it on record.
A woman, aged 21, unmarried, came