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Article
July 1926

GRANULOMA INGUINALE: CLINICAL OBSERVATIONS, VACCINE TREATMENT AND ALLERGIC REACTIONS

Arch Derm Syphilol. 1926;14(1):14-27. doi:10.1001/archderm.1926.02370190027004
Abstract

REVIEW OF THE LITERATURE  Conyers and Daniels1 were the first to describe granuloma venereum as a clinical entity, and they considered it to be a form of lupus. In 1897, Galloway2 first called it granuloma inguinale and gave a good description of the pathologic changes. Good clinical descriptions have been given by many writers since that time, including Maitland,3 Aragao and Vianna,4 Pijper,5 Schochet,6 and Goodman,7 who called attention to the frequency of the disease in the United States.Histologic descriptions were given by Galloway,2 Campbell,8 Schochet,6 and Flu.9 In our opinion, the last author has given the most detailed and accurate description of the pathology.Wise10 and Maitland3 thought that the disease was caused by a spirochete; LeDantec11 and Conyers and Daniels1 believed it to be a form of tuberculosis; Rabello12 considered it

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