A dermatitis affecting infants almost exclusively, limited to the diaper area, and consisting of an erythematous, papular or papulovesicular eruption, frequently with superficial erosions, has long been recognized as a clinical entity. Since Jacquet's excellent description of this condition in 1886 differentiated it from hereditary syphilis with which it had formerly been frequently confused, the eruption has been designated by many dermatologists as "jacquet dermatitis." Although the etiology was obscure to the earlier observers, it became evident later that the condition was more or less frequently accompanied by the presence of ammonia in the diapers of the affected infants, and, in recent years, pediatricians, who see the lesions relatively frequently, have considered it an ammonia dermatitis and have confirmed its constant association with "the ammoniacal diaper." The origin of the offending ammonia in infants' diapers was the subject of considerable speculation, and, while various measures resulted in the temporary amelioration
COOKE JV. XLIX.—DERMATITIS OF THE DIAPER REGION IN INFANTS (JACQUET DERMATITIS). Arch Derm Syphilol. 1926;14(5):539–546. doi:10.1001/archderm.1926.02370230040003
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