[Skip to Content]
[Skip to Content Landing]
December 1926


Arch Derm Syphilol. 1926;14(6):713-714. doi:10.1001/archderm.1926.02370240080008

In the English and American literature there is a striking paucity of references to the so-called "fixed arsphenamine dermatitis," cases having been reported only by Moore and Keidel1 and Stokes and Cathcart.2

The first description of this condition was given by Naegeli3 in 1917. Following this article there came similar reports from Fuchs,4 Engweer and Josephson,5 Thibierge and Mercier,6 Schöfeld,7 Leibkind,8 Kraus9 and Levin.10

The patient who is the subject of the following case report was seen by my associate, Dr. F. J. Eichenlaub, in a clinic in 1920 and was brought to the office by him for observation.

REPORT OF CASE  A white woman, aged 34, sought relief, in 1920, for a circinate nodular syphiloderm situated on the outer aspect of the right forearm about midway between the wrist and the elbow. The Wassermann reaction was strongly positive. Following