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March 1927


Arch Derm Syphilol. 1927;15(3):361-363. doi:10.1001/archderm.1927.02370270122011

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Colloid Degeneration. Presented by Dr. Wile.  Mrs. K. F., aged 47, a Russian x=Jewess, had first noticed a lesion of the mid-forehead fifteen years previously, following trauma. At first there was a painful nodule, which almost entirely disappeared, and then gradually enlarged, attaining the size of a large coin. There had not been any increase in size for five years prior to the time of presentation, or any subjective symptoms. The nodule was flat, sharply outlined and of a dull erythematous color, with small blood vessels visible on the surface. It was fairly firm. The biopsy study revealed epidermic atrophy, numerous sebaceous cysts and colloid degeneration of the connective tissue.

DISCUSSION  Dr. Breitenbach: Under the microscope, the colloid degeneration was clearly evident.Dr. Jamieson: Clinically, the lesion resembled a sarcoid.Dr. Wile: Sarcoid was the original diagnosis, but the histologic study disproved it.

Epithelioma of the Lip. Presented by Dr. 

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