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April 1927


Arch Derm Syphilol. 1927;15(4):511-515. doi:10.1001/archderm.1927.02370280127011

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Localized Hyperhidrosis. Presented by Dr. Tobias.  E. H., aged 21, had suffered for the last two years with a condition which began with increased perspiration affecting the back of the left foot. The skin of the involved area then became red and macerated from the continuous oozing of sweat. The perspiration was so marked that it affected the stocking and lining of the shoe. At presentation, the lesion was about the size of a silver dollar. The overlying skin was glazed and covered with large beads of sweat. The lesion was well demarcated, the border showing signs of active inflammation.

DISCUSSION  Dr. Tobias: My diagnosis of localized hyperhidrosis was based on the history and the local appearance of the lesion. I could find nothing definite as to the cause of the condition. Careful examinations have been made from the standpoint of nerve involvement and vascular disturbance, but all results have

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