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June 1927


Author Affiliations


From the Department of Medicine of Western Reserve University and Lakeside Hospital.

Arch Derm Syphilol. 1927;15(6):652-658. doi:10.1001/archderm.1927.02370300008002

In 1872 Bäumler1 described intermittent quotidian fever in tertiary syphilis, and reported several cases. Bäumler states that P. G. Werlhof (1732), Joseph Frank (1821), Prosper Yvaren (1854) and Wunderlich (1870) recognized febris quotidiana syphilitica, and appreciated both the value of mercury and the inadequacy of quinine in the treatment of the disorder. According to Thayer,2 Sir William Jenner observed that when quotidian chills and fever do not yield to other treatment, they may to potassium iodide. The literature of the last quarter-century contains numerous relevant communications, including, among others, noteworthy contributions by Thayer,2 Bialocour,3 Janeway,4 Bassett-Smith,5 Morgan,6 Futcher,7 McKenna,8 Imhof-Bion,9 Huber,10 Scherck,11 Siebert,12 Jordan,13 Stern14 and Taussig.15 Excellent bibliographies are to be found in the last four papers.

In one of Futcher's cases the pyrexial onset took place twenty-nine years after the chancre was

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