Keratoderma blennorrhagicum is a rare skin disease. Only seventy cases are on record, of which eleven have been described in the American literature. In the following article, we have endeavored to clarify the confusion that still exists regarding pathogenesis, nomenclature and relationship to other similar eruptions.
Buschke,1 in his monograph published in 1899, divided all gonorrheal manifestations on the skin into four groups: (1) simple erythemas, (2) urticaria and erythema nodosum, (3) hemorrhagic and bullous exanthems and (4) hyperkeratoses. This classification, though slightly schematic, has been generally accepted. The most important and characteristic group is the one of gonorrheal hyperkeratoses. On the basis of carefully studied cases, Buschke concludes that the hyperkeratoses should be strictly separated from other gonorrheal manifestations and should be classified as a separate clinical and histologic entity. The reasons supporting his conclusions are as follows: First, there are no transitory clinical or histologic manifestations which
ROSTENBERG A, SILVER H. KERATODERMA BLENNORRHAGICUM: CRITICAL REVIEW WITH A REPORT OF A CASE. Arch Derm Syphilol. 1927;16(6):741–753. doi:10.1001/archderm.1927.02380060060005
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