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July 1928


Arch Derm Syphilol. 1928;18(1):121-130. doi:10.1001/archderm.1928.02380130124012

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As it seems highly probable that some of the substances to which the body can be sensitized are not protein in nature, it is better to speak of the resultant reaction as allergic.

ALLERGIC DISEASES  The diseases which should be included in this list are the following:

  1. Allergic dermatitis, which may be either local or general.

  2. Urticaria.

  3. Erythema multiforme.

  4. Purpura.

  5. Neurodermite and some cases of simple lichenification.

  6. Some cases of rosacea.

  7. Dermatitis herpetiformis.

  8. Infantile eczema.

Allergic Dermatitis.—  A brief description of allergic dermatitis, neurodermite and lichenification is advisable in order that there may be no doubt as to the conditions described.Allergic dermatitis is usually characterized by the recurrence of attacks. The intervals between attacks vary from one week to a number of years. The portions of the body involved are usually the face, neck, upper portions of the chest and the back, and the hands and arms. Frequently, covered portions of the body may be affected. The rash usually starts as a macular one, but later it may be maculopapular, papular or even vesicular, and still later the lesions are often frankly squamous. In severe cases, oozing almost invariably occurs. At the onset there are numerous discrete lesions, but these usually become confluent. The color varies from pale pink to deep red.

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