Reports of comparative tests of various serologic procedures applied to identical specimens of serum are already abundant in the literature on syphilis. Opinion concerning the significance of such comparisons in regard to the choice of technical method is by no means unanimous. In fact, one gains the impression that more helpful results are obtained by complement-fixation at the hands of some workers, while for others, precipitation or the precise measurement of flocculation appears more useful. The identification of each technical procedure by the name of an individual investigator is apparently unavoidable, but this lends a personal quality to the rivalry of these various methods in their claim on the attention of the clinician. At present, for the most satisfactory results, the serum of the patient should be examined by several methods. When this is not practicable, the choice of procedure is often determined by the relative cost and availability of
SHEPLAR AE, LYONS MA, MacNEAL WJ. SEROLOGIC DISCORD IN LATENT AND TREATED SYPHILIS: REPORT OF CASES. Arch Derm Syphilol. 1928;18(5):742–754. doi:10.1001/archderm.1928.02380170098010
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