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December 1928


Arch Derm Syphilol. 1928;18(6):981-990. doi:10.1001/archderm.1928.02380180178022

Lupus Erythematosus: Unfavorable Response to Gold Therapy. Presented by Dr. Eller.  E. M., a married woman, aged 27, from the Post Graduate Skin Clinic, presented a brownish, erythematous, scaly eruption involving the bridge of the nose and adjoining areas of the cheeks. There had never been any lesions elsewhere. This was a typical lupus erythematosus discoid, of eleven years' duration. She was first seen in August, 1927. Prior to this she had received several types of treatment, including the roentgen ray, radium, carbon dioxide snow, quartz light and iodine with quinine. Atrophy, pigmentation and telangiectasia were present.She was given gradually increasing doses of gold and sodium thiosulphate twice weekly. At the end of the sixth treatment, a severe constitutional as well as a cutaneous reaction occurred, which latter involved the feet, eyes, mouth, lips, chest and face. The senses of smell and taste were greatly impaired, and the voice

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