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Article
February 1929

THE RÔLE OF IDIOSYNCRASY AND ALLERGY IN DERMATOLOGY

Arch Derm Syphilol. 1929;19(2):175-197. doi:10.1001/archderm.1929.02380200003001
Abstract

Until a short time ago, one understood that the term "allergic skin diseases" included those eruptions which occur during the course of certain infections, for example, tuberculosis or trichophytosis, when formed elements (tubercle bacilli, spores) are hematogenously distributed in an allergic skin. This allergy is brought about by the primary lesions (for instance, by a tuberculosis of the lymph glands or a kerion). One is justified in assuming that the local inflammatory reaction, which may even progress to necrosis, is due to the reaction of the antigen with the specifically sensitized skin. The individual lesion of the allergic dermatosis is the result of this local inflammatory process, and is called "tuberculid" in the case of tuberculosis and "trichophytid" in the case of trichophytosis. Even though certain phases of this process are still obscure and its essence is still not clear in many respects, no one doubts that this view of

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