The use of liquid oxygen in dermatology is not new; in fact, liquid air appears to have been the first agent used on the skin for refrigeration. It was first used in 1898, and during the next ten years there were a number of publications concerning it. A majority of those who used it were agreed that it was a worth while agent; but they doubted its practicability, as it could not be made commercially and could not be transported.
After Dr. William Allen Pusey,1 in 1907, suggested the substitution of carbon dioxide snow, liquid air was apparently soon forgotten, and little mention was made of it after 1910.
Since the manufacture of oxygen gas has been made an important industry, liquid oxygen is available in all these plants and can be secured in at least seventy-five of the larger cities of the country at an average price of
IRVINE HG, TURNACLIFF DD. LIQUID OXYGEN IN DERMATOLOGY. Arch Derm Syphilol. 1929;19(2):270–280. doi:10.1001/archderm.1929.02380200098007
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