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Castellani's report in the December issue of the Archives should serve as a stimulus in the investigation of a difficult class of dermatoses which is continually presenting itself and which frequently remains unsolved as to etiology. Clinically, his case was of the order of cases often presented "for diagnosis" before dermatologic societies in the form of subacute or chronic, more or less suppurative, deep-seated dermatoses in which it seems possible to eliminate, both clinically and by laboratory tests, tuberculosis, syphilis and fungus infection in causation. The tropical phagedenic ulcers might be added here. Fortunately, such additional circumstances as the distribution, clinical course and, to a limited but still frequently important extent, the laboratory examinations, remove deficiencies which clear up the entire matter; but only too often the dermatologist is reduced to the extreme of symptomatic diagnosis instead of the etiologic, which is the ideal.
It must be self-evident that the
GRANULOMAS FOR DIAGNOSIS. Arch Derm Syphilol. 1929;19(2):284–285. doi:10.1001/archderm.1929.02380200112009
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