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Article
June 1929

SCLERODERMA: WITH SPECIAL REFERENCE TO ITS ETIOLOGY AND TREATMENT

Author Affiliations

BOSTON

From the Department of Diseases of the Skin, Boston City Hospital.

Arch Derm Syphilol. 1929;19(6):901-916. doi:10.1001/archderm.1929.02380240036004
Abstract

The early history of scleroderma is confused with that of leprosy, ichthyosis and keloid. Under the name of ichthyosis corii, Curzio,1 in 1752, described a case which was probably diffuse scleroderma. Alibert2 and Addison,3 under the name of true keloid, distinguished the localized form of scleroderma from false keloid, the latter being what is now called keloid. Henke4 described the infantile form of the disease clearly and in a footnote gave a typical case of the diffuse type in the adult. He called it Verhaertung des Zellgewebes or induratio telae cellularis. Fagge5 reported an interesting postmortem examination of the skin and liver in a case of diffuse "scleriasis." T. C. Fox6 gave an interesting account of the early history of the disease. In 1895, Lewin and Heller7 reviewed the whole subject up to that date, collecting reports of more than 500 cases from

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