While individualization should be practiced in the treatment of patients with syphilis, the therapeutic procedure is based on an evaluation of the various remedies employed and a personal selection of them for routine treatment.
I have had a rather extensive correspondence in recent years on the subject of therapeutic accidents, and I have been impressed by the aggregate number of instances of serious and fatal complications that have come to my attention after the use of the arsphenamines. I have had the opportunity to compare the extent of the sequelae resulting from certain methods of treatment with those following other methods. To my mind, the guiding principle in the treatment for syphilis should be to employ remedies and methods which insure to the patient maximum curative effects against the disease with maximum security to the body tissues; and the latter is the more important of the two. This may appear
SCHAMBERG JF. BISMUTH AND NEOARSPHENAMINE IN SYPHILIS: AND A PLEA FOR MORE CONSERVATIVE DOSAGE OF THE ARSENOBENZENES. Arch Derm Syphilol. 1929;20(4):431–440. doi:10.1001/archderm.1929.01440040003001
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