In the course of a number of years during which many cases of leprosy have been observed, the general impression has grown that certain anatomic regions are exempt from leprous lesions. To determine the extent to which this general impression was correct, a survey of all the patients at the National Leprosarium was undertaken, and each of the regions presupposed to show some degree of immunity was examined.
In general, the surfaces of the skin investigated were those in which on account of the anatomic conformation some degree of protection is afforded from exposure to such irritants as sunlight, heat, cold, pressure or other causes tending to produce local hyperemia or erythema.
The impression prevailing before the survey was made was that the circinate lesions of maculo-anesthetic or nerve leprosy would not be found to conform in distribution with those of the skin type. The investigation, therefore, was limited to
HOPKINS R, DENNEY OE, JOHANSEN FA. IMMUNITY OF CERTAIN ANATOMIC REGIONS FROM LESIONS OF SKIN LEPROSY. Arch Derm Syphilol. 1929;20(6):767–779. doi:10.1001/archderm.1929.01440060003001
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