The past five years have witnessed an increasing interest in the functional and biochemical factors in the etiology of certain so-called toxic dermatoses. Studies involving careful examinations of the chemistry of the blood and tissues, the secretion of sweat, the involuntary nervous system and the gastro-intestinal tract have replaced much vague speculation with well established facts. The definite recognition that disturbances in the gastric secretion constitute a common underlying cause of acne rosacea, as pointed out by Ryle and Barber,1 Brown2 and others, has converted a hitherto obstinate disease into one which is reasonably amenable to treatment.
Using the fractional method of gastric analysis, Brown studied fifty cases of acne rosacea. The results of his study are shown in table 1.
Other investigators have reported essentially similar observations in acne rosacea, some showing even a larger percentage of cases in which hypo-acidity is present.
Brown also examined the
AYRES S. GASTRIC SECRETION IN PSORIASIS, ECZEMA AND DERMATITIS HERPETIFORMIS. Arch Derm Syphilol. 1929;20(6):854–859. doi:10.1001/archderm.1929.01440060090008
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.