The treatment for acute pemphigus by the use of an arsenical compound, iron cacodylate or sodium arsenate, given intravenously, and coagulen, given subcutaneously, devised by Dr. Robert H. Davis and the late Dr. William D. Davis, was the first advance ever made in the treatment for this disease, and has yielded a large proportion of recoveries in what had until then been an all but hopeless condition. This has been confirmed by reports from many parts of the country.
Any therapeutic procedure may fail at times. It was such a failure (case 1) that led me to essay a modification of the Davis treatment. Meeting with an unhoped for measure of success, I employed the modified method in four other cases.
This case has already been reported in detail.1 Briefly, it concerned a woman, aged 32, of previous excellent health. Three weeks before consulting me, in January,
GRINDON J. TRYPARSAMIDE IN ACUTE PEMPHIGUS. Arch Derm Syphilol. 1930;21(1):25–31. doi:10.1001/archderm.1930.01440070033003
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