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Carcinoma on a Gummatous Base. Presented by Dr. Amshel.
I. Y., a man, aged 39, married, was seen for the first time on September 14. He presented a hard, crusted ulceration of two years' duration, with a suggestion of a rolled border involving almost the entire left side of the lower lip. The patient said that he had a chancre about twenty years before presentation and was treated locally. About a month later, he had a generalized rash. A Wassermann reaction taken about a year prior to presentation was negative, but the patient received treatment consisting of two intramuscular injections and six intravenous injections, without any change in the lesion on the lip. A Wassermann reaction taken a week before presentation was also negative. The patient had just received one injection of neoarsphenamine and two injections of bismuth without any change. The cervical glands were not enlarged.
Willard L, Phillips HT. PITTSBURGH DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1930;21(2):338–341. doi:10.1001/archderm.1930.01440080178022
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