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Article
September 1930

THE RESPONSE OF SEROLOGIC TESTS TO TREATMENT: WITH SPECIAL REFERENCE TO EARLY SYPHILIS

Author Affiliations

PHILADELPHIA

From the Department of Dermatology and Syphilology, University of Pennsylvania, School of Medicine, and the Syphilis Clinic of the Hospital of the University of Pennsylvania, Dr. John H. Stokes, director.

Arch Derm Syphilol. 1930;22(3):470-482. doi:10.1001/archderm.1930.01440150096010
Abstract

In previous communications,1 our efforts were directed toward a comparison of the Kolmer Wassermann test and the Kahn precipitation test against known clinical data, irrespective of treatment, and our percentage of agreements was low in comparison with that of other investigators. Our present study is confined to a known group of syphilitic patients compared both before treatment and throughout treatment to the persistently negative serologic phase, or in a small group to serologic relapse or Wassermann-fastness.

MATERIAL AND METHODS 

Patients.—  The material for this study comprised one hundred and five syphilitic dispensary patients, eighty-three with early and twenty-two with latent infections, on whom 910 serologic examinations were made, including both the Kolmer Wassermann and the Kahn precipitation tests on identical serums. Patients were included whose treatment began subsequent to January, 1927, the time at which we started the routine use of the Kahn test in addition to the Kolmer

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