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September 1930


Arch Derm Syphilol. 1930;22(3):520-529. doi:10.1001/archderm.1930.01440150146016

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Silver Arsphenamine Argyria (Two Cases). Presented by Dr. Spiegel.  F. B., aged 54, said that he had been treated for gonorrhea nineteen years previously. He had received three intravenous injections for syphilis twelve years before presentation.The patient first came under observation on Dec. 10, 1925, for treatment for tabes. The symptoms consisted of pains in the legs, anisocoria, Argyll Robertson pupils, positive Romberg sign, absence of deep reflexes and paresthesia of both legs. The Wassermann tests of the blood and spinal fluid gave negative results. There were 8 cells, and the globulin test gave negative results. The colloidal gold test gave a reaction of 00023320000. From Dec. 10, 1925, to Nov. 5, 1926, he received a course of treatment with injections of arsphenamine, mercury and bismuth. From May 25, to Dec. 29, 1927, he received a course of treatment with silver arsphenamine and bismuth. From March 7, to Dec. 28, 1928, he received two courses of treatment consisting

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