The introduction of drugs into the human body by means of an electric current has fascinated medical physicists for more than a century. According to Turrell,1 ionic medication was enunciated as long ago as 1747 by Veratti. Jones2 stated that Palaprat claimed to have introduced iodine into the tissues in this way in 1833. There are an increasing number of references in the literature since this date: Richardson, 1859; Burns, 1870; Mink, 1873, and Gauthier, Morton, Edison and Foveau de Cournelles in the early nineties. The idea, however, was imperfectly understood and consequently failed to attract attention and made no progress. The general application of the theory, as a practical question in therapeutics, must be credited to Leduc, who, in a series of papers beginning in 1900, brought it forcefully before the medical profession. Considerable literature on the subject has accumulated since this date.
One hesitates to announce
SHAFFER LW. IONIC MEDICATION IN DERMATOLOGY: PRINCIPLES, EXPERIMENTAL CONFIRMATION AND CLINICAL APPLICATION. Arch Derm Syphilol. 1931;23(2):287–308. doi:https://doi.org/10.1001/archderm.1931.03880200077006
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