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February 1931

La pratique médicale Illustrée. Les traitements modernes de la paralysie générale

Arch Derm Syphilol. 1931;23(2):401. doi:10.1001/archderm.1931.03880200191021

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This monograph is devoted largely to the use of stovarsol or acid-acetyl-oxyamino-phenyl-arsinic in dementia paralytica. This drug was introduced by Louis Fournier and Levaditi. It is given by mouth or subcutaneously. The authors have employed the skin route, the dose being 1 Gm., given three times weekly, for a total of twenty-one treatments. Their conclusions are as follows: "After a study of our statistics, it would seem that in its present form, the stovarsol treatment for dementia paralytica is a simple method, without danger, which ameliorates the condition of these patients in the proportion varying from 68, 58 or 26 per cent, depending on whether one is dealing with the form with excitation, dementia paralytica plus diminished intellect or the type with complete dementia. This drug rarely restores the cerebrospinal fluid to normal." The authors compare their method with the malarial treatment in the following words, "Therefore, if we may

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