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Article
May 1931

EXPERIMENTAL SYPHILIS IN RABBITS: II. A COMPARATIVE STUDY OF THE KAHN AND WASSERMANN REACTIONS

Author Affiliations

CHICAGO

From the Physiological Laboratory of the University of Chicago.

Arch Derm Syphilol. 1931;23(5):856-862. doi:10.1001/archderm.1931.03880230030002
Abstract

In the first article1 we drew the following conclusions: The Kahn test is negative in 95 per cent of nonsyphilitic rabbits and the Wassermann in 100 per cent. The Kahn and Wassermann reactions are parallel with the intensity of the syphilitic involvement. Kahn and Wassermann reactions are negative in latent experimental syphilis in rabbits. Treatment that modifies the course of experimental syphilis also modifies the Kahn and Wassermann reactions. The Kahn reaction is more sensitive than the Wassermann, as evidenced by its tendency to become positive earlier and remain positive longer. The Kahn test is somewhat more desirable than the Wassermann for use in the study and the treatment of experimental syphilis in rabbits.

METHOD  The technic and interpretation of the quantitative Kahn test were exactly the same as those employed in the previous work,1 and the same person performed the tests. Virtually the same technic was used

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