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May 1931


Author Affiliations

Ancker Hospital, St. Paul

Arch Derm Syphilol. 1931;23(5):1008-1013. doi:10.1001/archderm.1931.03880230184024

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Granuloma Annulare. Presented by Dr. C. D. Freeman.  Miss S. presented lesions that began one year before presentation on the right elbow as deep-seated infiltrations of the skin. Her past history was unimportant. At the time of presentation there were lesions on both arms and on the right thigh. The nodules were not crescentic or circinate, but were more or less irregularly arranged, and involution had taken place in some of the lesions. The biopsy specimen showed a decided cellular infiltration with lymphocytes, polymorphonuclear leukocytes and proliferative connective tissue cells in the subpapular layer. Necrosis was present in the center of some of the infiltrated areas.The patient's father and mother died of tuberculosis, the mother having contracted it from the father. Her brothers and sisters were well.

DISCUSSION  Dr. C. D. Freeman: When I first saw the case I thought that the condition was sarcoid, but a diagnosis of

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