In spite of the fact that it is not uncommon to observe both atrophic and hyperkeratotic lesions in the skin of pellagrins following the acute stages of the disease, the development of epitheliomas in such cases apparently occurs with surprising infrequency; because of this, and because of the extreme rapidity with which the epithelioma developed in the following case, it seems that the case is sufficiently unusual to merit reporting.
Examination of the literature covering the publications of the past fifteen years revealed only two analogous cases, both of which were reported by Lynch1 in 1917. The first occurred in a colored woman, 22 years of age, who was brought to the hospital in the terminal stage of pellagra, and who died two days after admission. At autopsy, a section from the edge of a superficial, palm-sized ulcer on the inner aspect of the thigh disclosed an epitheliomatous hyperplasia
RUTLEDGE WU, KELLY R. AN EPITHELIOMA SECONDARY TO PELLAGROUS DERMATITIS. Arch Derm Syphilol. 1931;23(6):1072–1075. doi:10.1001/archderm.1931.03880240053007
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