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Keratosis Palmaris et Plantaris. Presented by Dr. Louis Tulipan.
W. C., a white boy, aged 12 years, weight 150 pounds (68 Kg.), whose mother and father were first cousins, was evidently suffering from a pituitary dystrophy (Frölich syndrome). His palms showed scattered pea-sized keratotic lesions. The heels and soles disclosed heavy, horny masses. All of the nails were dystrophic with hyperkeratosis and discoloration and curving.
Dr. Oscar Levin: The skin shows mainly keratotic lesions of the palms and soles with dystrophy of the nails. Other cutaneous evidences as well as signs in other structures suggest dysfunction of the pituitary gland. As a result of a cursory examination, I believe that the patient is suffering from Frölich's syndrome. The changes in the skin are merely external manifestations of the general condition.
Dr. Herman Sharlit: The patient is suffering from a pituitary dystrophy (Frölich's type), and patients so afflicted frequently present
Cannon AB, Highman WJ. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILOLOGY. Arch Derm Syphilol. 1931;24(1):140–151. doi:10.1001/archderm.1931.01450010145016
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