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August 1931


Arch Derm Syphilol. 1931;24(2):196-203. doi:10.1001/archderm.1931.01450010203003

In this study five types of genetic hairlessness have been examined histologically : a dominant hairless mutation in the house mouse,1 and a recessive mutation in the house mouse,2 the deer mouse,3 the rat4 and the rabbit.5 In addition, a case of hairlessness, apparently inherited although of undetermined genetic nature, has been examined in a house mouse3 from Cold Spring Harbor, N. Y. The object was to determine the histologic changes occurring in the skin, to trace and compare the development of these abnormalities and to determine if there was any relation between the histology and the type of inheritance.

Of the reports in the literature on hairlessness, that of a hairless goat given by Bonnet6 and the cases in human beings described by Unna7 are of especial interest in the present study. The former is similar to the histologic condition found in