The phenomenon of myxedema occurring in circumscribed areas of the skin promises to afford a means of shedding some light on the mystery of the influence of the glands of internal secretion on the skin. English and American medical literature contains but few reports of this condition, and it would seem worth while to record a case that has come under the observation of Dr. Stokes and to attempt a critical evaluation of the diagnostic criteria advanced by various investigators.
REPORT OF CASE
History.—Miss H. U., aged 36, a minister, in February, 1924, noted typical symptoms of hyperthyroidism including nervousness, precordial throbbing and palpitation, stridor and hoarseness. The basal metabolic rate was plus 55. At operation the thyroid was found to be uniformly enlarged, and a subtotal thyroidectomy was performed. The period of convalescence was stormy, and the marked hoarseness, which was noted immediately after operation, did not
PILLSBURY DM, STOKES JH. CIRCUMSCRIBED MYXEDEMA OF THE SKIN. Arch Derm Syphilol. 1931;24(2):255–270. doi:10.1001/archderm.1931.01450010262009
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