Extramammary Paget's disease associated with carcinoma of the skin has been reported many times. Authors and discussors of the cases have usually held that the carcinoma is glandular, arising in the epithelium of the sudoriferous or sebaceous glands. We shall report a case of extramammary Paget's disease in which there was a central carcinoma of the epidermoid, individual cell, keratinizing type, and we shall sum up some of the evidence in an effort to show Paget's disease as a true precancerous lesion. This disease is a response to carcinogenic agents, that is, it is a definite lesion, which is one stage in the progressive evolution of normal skin to true carcinoma.
REPORT OF CASE
History.—E. B., a colored man, aged 46, single, presented himself at the skin clinic of the Mercy Hospital, on March 8, 1929, with a lesion on the dorsal surface of the glans penis.
BUSMAN GJ, WOODBURNE AR. PAGET'S DISEASE OF THE GLANS PENIS: WITH CENTRAL CARCINOMATOUS DEGENERATION. Arch Derm Syphilol. 1931;24(3):396–400. doi:10.1001/archderm.1931.01450010405005
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: