Our attention was first called to the possibility of unequal amounts of bismuth in measured doses of oily bulk bismuth suspension when working with tartroquiniobine. This is a suspension of the iodobismuthate of quinine and of sodium potassium bismuth tartrate in camphorated oil and has a metallic bismuth content of 6 cg. per two cubic centimeters. Because of the time required when doses are put up in separate ampules, as well as because of the expense, we used this preparation in 25 cc. amounts put up in wide-mouthed shallow bottles. The bottles were thoroughly shaken before the dose was removed; moreover, the suspension contained several glass beads to assist in more thorough mixing. At the bottom of the bottle we were occasionally surprised to find a heavy, thick, reddish deposit. This disturbing factor led us to examine several other bulk products that we were using, the potassium bismuth
COLE HN, HENDERSON KI, von OETTINGEN WF, SOLLMANN T. THE PRESENCE OF UNEVEN QUANTITIES OF BISMUTH IN OILY BULK SUSPENSION OF BISMUTH SALTS. Arch Derm Syphilol. 1931;24(5):739–744. doi:10.1001/archderm.1931.01450010751004
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