Case 1.—An elderly woman was referred to me by her physician because she had a warty growth on the right cheek (fig. 1). The tumor was of three months' duration. It presented a central protuberant keratotic mass set in a fleshy base, and suggested the appearance of an early cutaneous horn. The growth was freely movable with the skin and but slightly infiltrated it. There was no evidence of infection or inflammation. No adenitis could be appreciated. In spite of the apparently long duration of the tumor and the absence of lymphatic invasion, I had no doubt but that we were dealing with a slow-growing, squamous carcinoma (epithelioma). The biopsy confirmed my diagnosis. Further examination of the patient's face revealed on her forehead, and partly covered by her hair, a little tumor, of a week's duration, which was the color of the surrounding skin and slightly raised above its surface.
SAVATARD L. EARLY EPITHELIOMA. Arch Derm Syphilol. 1931;24(5):835–841. doi:https://doi.org/10.1001/archderm.1931.01450010847009
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