It has long been known that the darker-skinned races are sometimes affected with leukoderma. Such stories as the one occasionally heard of the "Negro who turned white" no doubt originated from the rare cases of extensive depigmentation.
The following is apparently the first report of a case of complete leukoderma :
A mulatto, aged 55, came to the medical service complaining of pain in both knees, following an old bilateral compound fracture of both legs with resultant bowing. His peculiar white appearance at first suggested an unusually severe anemia, although he was not weak or short of breath and the mucous membranes were of good color. The blood was reported to be normal, and the Hinton, Wassermann and Kahn tests were also negative.
The patient then volunteered the following explanation for his whiteness: Until the age of 35, he had the ordinary brown skin of a mulatto. At that time, following a scratch on the
GOLDEN LA. COMPLETE LOSS OF PIGMENT IN THE SKIN OF A NEGRO: A CASE OF COMPLETE LEUKODERMA. Arch Derm Syphilol. 1931;24(6):1069–1070. doi:10.1001/archderm.1931.01450011086009
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