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Gumma with MalignantDegeneration. Presented by Dr. H. F. DeWolf.
E. S., a man, aged 64, from the City Hospital service of Dr. H. N. Cole and Dr. J. R. Driver, had cut his left leg on a piece of glass eight years prior to presentation. The wound had healed, and three years later had broken down spontaneously, the lesion progressively enlarging. A few months before presentation, a piece of bone had been removed from the lesion. There was no history of venereal disease, although antisyphilitic treatment had been administered. The Wassermann reaction was strongly positive, but the lesion did not seem to have been influenced by four injections of arsphenamine.
There was an ulcer, about 8 cm. wide and 15 cm. long on the lateral and posterior aspect of the upper and middle third of the left leg. The superior and inferior borders were rolled and indurated; the
Parkhurst HJ. CLEVELAND DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1931;24(6):1137–1141. doi:10.1001/archderm.1931.01450011154018
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