Since the advent of roentgen rays in dermatologic therapy, their direct action having been utilized in the treatment of cutaneous lesions for more than thirty years, repeated efforts have been made to extend their field of usefulness. When direct roentgen action has failed or has been found unsatisfactory, and when other means of treatment have not proved wholly successful, methods have been sought that might strike at the pathogenesis of the disease or that might be effective by acting indirectly on biologic or physiologic activities. Examples of this type of roentgenotherapy are the Brock method of irradiating the thymus region in psoriasis and the treatment for lupus erythematosus by irradiation of the regional lymph nodes. Indirect roentgenotherapy has been directed to the thyroid, the ovaries, the hypophysis, the liver, the spleen, the suprarenal glands, the vegetative nervous system, the spinal cord, its roots and ganglions, and large cutaneous fields.
FOERSTER HR. ROENTGENOTHERAPY OF THE SPINAL REGION IN DERMATOLOGY. Arch Derm Syphilol. 1932;25(2):256–279. doi:10.1001/archderm.1932.01450020268005
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