Previous to the study by Michelson and Allen.1 practically all the literature on so-called acne conglobata concerned itself with the minutiae of clinical and pathologic description, with a discussion as to its relationship to other pyodermias, and with the attempt to fasten on it a tuberculous etiology. Because of the shortness of time and because this literature has little in common with this experimental study, other than in name, only two previous publications will be reviewed. For the bibliography on the subject, the interested reader is referred to the study mentioned.
In 1924, Strumia2 published a report, under the name "Experimental Acne Varioliformis," of experimental work carried out in a case of chronic, resistant pyodermia. From the clinical description, this case does not quite fit acne conglobata, but I believe that it is closely related and, in view of this work and that published by
BELOTE GH. ACNE CONGLOBATA: AN EXPERIMENTAL STUDY. Arch Derm Syphilol. 1933;27(2):302–311. doi:10.1001/archderm.1933.01450040307012
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