Barber and Oriel have called attention in three articles to their investigations on urinary proteose in dermatoses. Their article in the Lancet, written in 1930,1b contains detailed information on the application of this work to dermatology.
In this article, the following essential information is brought out:
If the urine from cases of allergic and febrile diseases is acidified with sulphuric acid and shaken with a fifth of its volume of ether, the ethereal layer formed on standing, instead of being for the most part clear, as in normal people, becomes opaque, and has a waxy appearance. In strongly positive cases we noted that the tube could be inverted without spilling the contents.
The method of preparing the proteose is described as follows:
A twenty-four hour specimen of urine is collected from a case showing active symptoms, and put in a Winchester bottle containing a little chloroform. Approximately