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Article
June 1933

FATALITY AFTER INTRAMUSCULAR INJECTION OF BISMUTHIN A MAN SENSITIVE TO ARSENOBENZENES

Arch Derm Syphilol. 1933;27(6):969-970. doi:10.1001/archderm.1933.01450040979008

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Abstract

In a recent work entitled the "Treatment of Syphilis," we commented on the relative safety and harmlessness of bismuth compared with the arsenobenzenes and mercury. Furthermore, in clinic and office work we have given about 75,000 injections of bismuth without a single serious manifestation or symptom of intoxication. Beerman (Arch. Dermat. & Syph.26:797 [Nov.] 1932) recently reported 35 deaths due to bismuth in the treatment of syphilis, collected from the literature since 1922. To this number we add a death which we regard as unusual.

A man, aged 51, presented a florid secondary syphilis at the time of the first examination, and in accordance with our usual therapeutic policy, treatment was instituted with an intramuscular injection of 100 mg. of bismuth salicylate. During his examination he rested one hand on a table where neoarsphenamine had been mixed for a preceding patient and came in contact with a few

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