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Ichthyosis Hystrix. Presented by Dr. J. P. Guequierre.
A schoolgirl, aged 17, complains of thickening of the skin of the extremities. The skin is generally somewhat dry and ichthyotic, but the patient perspires freely on the palms and soles. Over both upper and lower extremities there is a dirty grayish hyperkeratosis, which is marked over the extensor surfaces of the ankles, knees and buttocks, where it forms closely set spicules and warty papillary elevations. The margins of the patches are ill defined. The hyperkeratosis is less marked on the extensor surfaces of the wrists and on the dorsa of the hands and elbows, but it is thick enough to accentuate and coarsen the normal lines of the skin. The flexor surfaces of the extremities are relatively free. There are several light areas of relatively normal though dry skin in the midst of the hyperkeratotic fields, which are apparently the sites
Gilman RL, Weidman FD. PHILADELPHIA DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1933;28(4):582–589. doi:10.1001/archderm.1933.01460040125017
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