The question of the tuberculous etiology of lupus erythematosus has created an extensive controversial literature. As a result of a clinicopathologic study of approximately 20 cases of lupus erythematosus which came to necropsy, I was impressed by the lack of evidence of active tuberculosis in the modern sense. Among European dermatologists there is still a difference of opinion. In general, the French, Austrian and Swiss observers have attributed the disease to tuberculosis, whereas the English have stressed the rôle of the streptococcus. The German school favors the conservative theory of multiple etiology advocated by Jadassohn. American dermatologists are divided in their opinions, as was demonstrated by a recent discussion.1
In studying the reported necropsies, I found that only 20 per cent of 125 postmortem examinations performed on patients with lupus erythematosus showed active or possibly active tuberculosis (bibliography), in contrast with the much higher frequency of association recorded by
KEIL H. RELATIONSHIP BETWEEN LUPUS ERYTHEMATOSUS AND TUBERCULOSISA CRITICAL REVIEW BASED ON OBSERVATIONS AT NECROPSY. Arch Derm Syphilol. 1933;28(6):765–779. doi:10.1001/archderm.1933.01460060002001
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