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Article
December 1933

QUANTITATIVE ESTIMATES OF HYDROGEN SULPHIDE IN LOTIONS USED IN TREATMENT OF ACNE

Author Affiliations

NEW YORK

From the Stuyvesant Square Hospital, formerly the New York Skin and Cancer Hospital.

Arch Derm Syphilol. 1933;28(6):847-854. doi:10.1001/archderm.1933.01460060084015
Abstract

After many months of qualitative tests for hydrogen sulphide in lotio sulphurata1 and other medicaments used in the treatment of acne vulgaris, it was deemed advisable to proceed with a quantitative study. Considerable difficulty was experienced in determining the hydrogen sulphide content of the various lotions by means of the methods heretofore reported. However, from the basic principles of these methods, a procedure for the research was finally evolved. The results of the experiments, the qualitative studies previously made and the clinical results obtained were so in agreement that it is felt that a preliminary statement of the findings is warranted.

The theoretical considerations as to the usefulness of hydrogen sulphide in the pharmaceutic therapy of acne vulgaris, as well as the historical investigation, will not be discussed in this report.

A description of the methods used in the chemical studies will be reserved for a later paper. The

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